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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T22958 | M 25 | Others | |
M 25 is a Smoothened (Smo) receptor antagonist. | |||
T71299 | M-25 | ||
M-25 is a Smoothened antagonist and inhibitor of the Hedgehog pathway. | |||
T14197L | Alvameline maleate | Lu 25-109-M | |
Alvameline maleate is used as a Partial M1 Agonist and M2/M3 Antagonist. | |||
T18173 | M-PEG25-acid | Others | |
m-PEG25-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system with... | |||
T18174 | M-PEG25-Hydrazide | Others | |
m-PEG25-Hydrazide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system... | |||
T18176 | M-PEG25-Propargyl | Others | |
m-PEG25-Propargyl is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system... | |||
T18175 | M-PEG25-NHS ester | Others | |
m-PEG25-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system... | |||
T71297 | TT15 | ||
TT15 is an agonist of the GLP-1R. | |||
T10432L | AZD-8529 mesylate | GluR | |
AZD-8529 mesylate is a highly selective, and orally bioavailable positive allosteric modulator of mGluR2 (EC50: 285 nM). It shows no positive allosteric modulator responses at 20-25 M on the mGluR1, 3, 4, 5, 6, 7, and 8 ... | |||
T38293 | 4-CPPC | Others | |
4-CPPC is an inhibitor of macrophage migration inhibitory factor-2 (MIF-2; IC50= 27 μM).1It is selective for MIF-2 over MIF-1 (IC50= 450 μM). It inhibits MIF-2, but not MIF-1, binding to CD74in vitrowhen used at a concen... | |||
T61928 | Antitubercular agent-25 | ||
Antitubercular agent-25 (Compound 28) is an anti-tubercular agent. Antitubercular agent-25 shows an extracellular IC50 of 0.42 μM and an intracellular IC50 of 0.20 μM against M. tuberculosis H37Rv. Antitubercular agent-2... | |||
T80300 | Aurein 2.6 | Antibiotic | |
Aurein 2.6, an antibiotic antimicrobial peptide, exhibits activity against various Gram-positive bacteria with minimum inhibitory concentrations (MIC) of 25, 25, 30, 25, and 30 μM for M. luteus, S. aureus, S. epidermis, ... | |||
T40317 | α/β-Hydrolase-IN-1 | ||
α/β-Hydrolase-IN-1 demonstrates exceptional potency, with MICs of 50 μM (25 μg/mL) against M. smegmatis and 16 μM (8.4 μg/mL) against M. tuberculosis H37Ra, establishing it as a superior compound in this class. | |||
T10432 | AZD-8529 | Others | |
AZD-8529 is a highly selective, and orally bioavailable positive allosteric modulator of mGluR2 (EC50: 285 nM). It shows no positive allosteric modulator responses at 20-25 M on the mGluR1, 3, 4, 5, 6, 7, and 8 subtypes. | |||
T38016 | Hirsutide | ||
Hirsutide is a cyclotetrapeptide fungal metabolite produced by the entomopathogenic fungus Hirsutella. It has antibacterial activity against C. pyogenes, S. aureus, P. aeruginosa, and K. pneumonia (MICs = 25, 13, 6, and ... | |||
T36330 | Terrecyclic Acid | ||
Terrecyclic acid is a sesquiterpene originally isolated from A. terreus with antibiotic and anticancer activity. It is active against S. aureus, B. subtilis, and M. roseus (MICs = 25, 50, and 25 μg/ml, respectively). Ter... | |||
T38152 | Gilvocarcin M | ||
Gilvocarcin M is an antibiotic originally isolated from S. gilvotanareus. It is active against S. aureus when used at a concentration of 32 μg/ml. Gilvocarcin M inhibits growth of KB cells (IC50 = 0.52 μg/ml) but has no ... | |||
T69629 | M‑89 MLL inhibitor | ||
M‑89 is a Highly Potent Inhibitor of the Menin-Mixed Lineage Leukemia (Menin-MLL) Protein−Protein Interaction (Kd = 1.4 nM; IC50 = 25nM). M-89 binds to menin with a Kd value of 1.4 nM and effectively engages cellular men... | |||
T35706 | 25-Desacetyl Rifampicin | ||
25-Desacetyl rifampicin is a major active metabolite of the rifamycin antibiotic rifampicin .125-Desacetyl rifampicin is active againstM. smegmatis(MIC99= 2.66 μM). 1.Kigondu, E.M., Njoroge, M., Singh, K., et al.Synthesi... | |||
T35500 | 3-epi-25-hydroxy Vitamin D3 | 3-epi-25-hydroxy Vitamin D3 | |
3-epi-25-hydroxy Vitamin D3is the C-3 epimer of 25-hydroxy vitamin D3.1Dietary administration of 3-epi-25-hydroxy vitamin D3(0.5 and 1 IU/g) decreases levels of serum parathyroid hormone (PTH) in male, but not female, we... |